Kakae M, Kawashita A, Onogi H, Nakagawa T, Shirakawa H. Bilateral Common Carotid Artery Stenosis in Mice: A Model
of Chronic Cerebral Hypoperfusion-Induced Vascular Cognitive Impairment.
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Watanabe H, Ikawa M, Kakae M, Shirakawa H, Kaneko S, Ono M. Synthesis and biological evaluation of
radioiodinated benzoxazole and benzothiazole derivatives for imaging myelin
in multiple sclerosis. Bioorg Med Chem Lett 103: 129691 (2024). doi: 10.1016/j.bmcl.2024.129691.
Kakae M, Nakajima H, Tobori S, Kawashita A, Miyanohara J, Morishima M, Nagayasu
K, Nakagawa T, Shigetomi E, Koizumi S, Mori Y, Kaneko S, Shirakawa H: The astrocytic
TRPA1 channel mediates an intrinsic protective response to vascular cognitive
impairment via LIF production. Sci Adv 9: eadh0102 (2023). doi: 10.1126/sciadv.adh0102. 【プレスリリース】
Takayama K, Tobori S, Andoh C, Kakae M, Hagiwara M, Nagayasu K, Shirakawa H, Ago Y, Kaneko S. Autism Spectrum
Disorder Model Mice Induced by Prenatal Exposure to Valproic Acid Exhibit
Enhanced Empathy-Like Behavior via Oxytocinergic Signaling. Biol Pharm Bull 45(8):1124-1132 (2022).
Nakajima H, Fujita S, Kakae M, Nagayasu K, Oh-Hora M, Shirakawa H, Kaneko S. Orai2 channel regulates
prostaglandin E2 production in TNFα/IL1α-stimulated astrocytes. Glia 70(9):1666-1680 (2022).
Watanabe H, Maekawa R, Iikuni S, Kakae M, Matsuo N, Shirakawa H, Kaneko S, Ono M. Characterization of Radioiodinated
Diaryl Oxadiazole Derivatives as SPECT Probes for Detection of Myelin in
Multiple Sclerosis. ACS Chem Neurosci 13(3):363-369 (2022).
Asao Y, Tobori S, Kakae M, Nagayasu K, Shibasaki K, Shirakawa H, Kaneko S. Transient receptor potential
vanilloid 4 agonist GSK1016790A improves neurological outcomes after intracerebral
hemorrhage in mice. Biochem Biophys Res Commun 529(3):590-595 (2020).
Kakae M, Tobori S, Morishima M, Nagayasu K, Shirakawa H, Kaneko S. Depletion of
microglia ameliorates white matter injury and cognitive impairment in a
mouse chronic cerebral hypoperfusion model. Biochem Biophys Res Commun 514(4):1040-1044 (2019).
Kakae M, Miyanohara J, Morishima M, Nagayasu K, Mori Y, Shirakawa H, Kaneko S.
Pathophysiological Role of TRPM2 in Age-Related Cognitive Impairment in
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Miyanohara J, Kakae M, Nagayasu K, Nakagawa T, Mori Y, Arai K, Shirakawa H, Kaneko S. TRPM2 Channel Aggravates CNS Inflammation
and Cognitive Impairment via Activation of Microglia in Chronic Cerebral
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Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S. Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide. Front Physiol 8:877 (2017).